The organism is likewise susceptible to high salt, high oxygen, and also reduced pH degrees. The toxin itself is quickly damaged by heat, such as in extensive cooking. The spores that generate the toxic substance are heat-tolerant and also will endure boiling water for an extensive time period. Over the following 3 decades, 1895-- 1925, as food canning was approaching a billion-dollar-a-year market, botulism was coming to be a public health hazard. The seven contaminant serotypes (A-- G) are typically separated by their antigenicity.